Microbiological Hydroxylation of Reichstein’s Compound S (17α-hydroxydesoxycorticosterone) bySclerotiniasp.;2β-Hydroxylation
نویسندگان
چکیده
منابع مشابه
Microbial hydroxylation of 16α, 17α-epoxyprogesterone by Penicillium decumbens
Microbial transformation has been successfully applied in the production of steroid intermediates with therapeutic use and commercial value in pharmaceutical industry due to its high regio- and stereo-selectivity. As such, it is still important to screen microbial strains with novel activity or more efficient abilities in the development of the commercial steroid industry. Biotransformation of ...
متن کاملMicrobial hydroxylation of 16α, 17α-epoxyprogesterone by Penicillium decumbens
Microbial transformation has been successfully applied in the production of steroid intermediates with therapeutic use and commercial value in pharmaceutical industry due to its high regio- and stereo-selectivity. As such, it is still important to screen microbial strains with novel activity or more efficient abilities in the development of the commercial steroid industry. Biotransformation of ...
متن کاملMicrobiological hydroxylation of cinerone to cinerolone.
Cinerone [2-(2'-cis-butenyl)-3-methyl-2-cyclopenten-1-one] is hydroxylated to cinerolone [2-(2'-cis-butenyl)-3-methyl-4-hydroxy-2-cyclopenten-1-one] by a number of streptomycetes, bacteria, and fungi. Aspergillus niger ATCC 9,142 and Streptomyces aureofaciens ATCC 10,762 were found to be the most effective hydroxylators. The optical activity of the product was found to range from [alpha](D) (25...
متن کاملMicrobial Hydroxylation of 16α, 17α-Epoxyprogesterone by Penicillium Decumbens
Microbial transformation has been successfully applied in the production of steroid intermediates with therapeutic use and commercial value in pharmaceutical industry due to its high regio- and stereo-selectivity. As such, it is still important to screen microbial strains with novel activity or more efficient abilities in the development of the commercial steroid industry. Biotransformation of ...
متن کاملMicrobiological aspects in the hydroxylation of estrogens by Fusarium moniliforme.
A strain of Fusarium moniliforme (IH4), isolated from soil, showed outstanding enzymatic abilities to hydroxylate a number of estrogens. Estrone and estradiol were transformed into the 15alpha-hydroxy derivatives, and estradiol 3-methyl ether was transformed into the corresponding 6beta-hydroxy derivative. Delta(6)-Estrone was not hydroxylated. The accumulation of 15alpha-hydroxyestrone was inf...
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ژورنال
عنوان ژورنال: Bulletin of the Agricultural Chemical Society of Japan
سال: 1958
ISSN: 0375-8397
DOI: 10.1080/03758397.1958.10857482